Van de Ven Double Halts Everton's Unbeaten Streak at Brand New Stadium
The Dutch defender became the initial defender to net two goals in a English top-flight match for Spurs since Jan Vertonghen in spring 2013.
At a glance
Micky Van de Ven heads into the net twice in opening period
The home side's Jake O'Brien has equalizer ruled after video check
Senegalese midfielder scores third in 89th minute
The defeat is the Merseyside club's initial at their new ground
The Tottenham defender scored on two occasions as Tottenham prolonged their unbeaten run on the road in the top division and handed Everton their first defeat at their new home.
The Toffees were unbeaten in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having departed their historic home behind after 133 years at the end of last season.
But Spurs captain the Dutchman pounced twice from corners in the first half to place their impressive record at risk, and they were unable to mount a comeback before Pape Matar Sarr - set up by former Toffees attacker the Brazilian - nodded in a third to seal the victory.
The Everton defender believed he had equalized the tally a short while after the defender's first goal, glancing a bullet header past the Spurs keeper from an set-piece.
The Portuguese striker, meanwhile, failed to convert a handful of opportunities, while Vicario made a succession of fine stops to ensure Tottenham went five away games without defeat in the English top flight.
But the VAR intervened, instructing Craig Pawson to review the goal on the screen and the official decided that the winger and the attacker were in offside positions and had impeded with the Spurs keeper.
The win elevates Thomas Frank's side into third place in the Premier League, a handful of points off north London rivals and table-toppers Arsenal.
The Merseyside club stay 14th and sit half a dozen points ahead of the relegation zone.
Tottenham analysis: Van de Ven excels in duties at each end of pitch
Following a drab weekday display in the Champions League against the French side, where they managed a only attempts on target, the manager opted for Randal Kolo Muani up front instead of ex-Everton forward the Brazilian.
The new arrival was unable to make much of an impact before being replaced for Richarlison after 60 minutes on the pitch, but it emerged he proved unnecessary in the end.
Defender the Dutchman transformed into an attacking force to be reckoned with.
Tottenham's first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur directing the ball back across the face of goal for an unmarked the defender to head home.
And Ven de Ven - filling in as skipper in Cristian Romero's absence - added his second in first-half stoppage time as he rose above the England keeper to nod in.
Van de Ven was equally impressive in defence, combining effectively with his defensive colleague as the duo handled excellently with the 34 crosses thrown their way by Everton.
Toffees breakdown: Toffees lacking striker's instinct
Everton's recent stadium had been a happy hunting ground, but it appears the novelty may have faded slightly and fans headed to the exits after Sarr's third for Spurs.
The end in the team's unbeaten home run will not be a major worry for David Moyes, but their striker situation are.
Beto and Thierno Barry - the Toffees' two established strikers - had netted just a single goal combined before the weekend's outing.
And they were failed to add to that poor record on a wet and gloomy evening on Merseyside.
Beto's form was epitomized when he chose to bicycle-kick a clear chance from near the goal, even with having space and time to readjust for a simpler attempt that would have challenged Vicario.
The substitute, as well, was unable to influence the game after coming on for Beto in the second half.
It wasn't for a lack of opportunity. Most of the home side's offensive moves came through Grealish and the forward, who tirelessly whipped dangerous balls into the Spurs penalty area.
Upcoming fixtures for these two sides?
The Toffees: The team head to the Stadium of Light in the top flight on early November at 8 PM.
Tottenham: Spurs go to Newcastle's ground on Wednesday, 29 October for their next round Carabao Cup match against Newcastle.